Performance & Mitochondrial

Peptides in this category relate to cellular energy production, mitochondrial function, and exercise-associated signaling. Research often examines pathways involved in how cells generate and use energy, adapt to physical stress, and regulate metabolism at the mitochondrial level. These compounds are discussed in educational contexts around endurance, metabolic efficiency, aerobic capacity, and the biology of exercise adaptation, with much of the evidence coming from preclinical and animal models and the degree of human data varying by compound.

• MOTS-C

  No human data

  MOTS-c is a 16 amino acid peptide encoded in mitochondrial DNA. Its metabolic and physical effects come from mice; in people it has been measured but not given in any cited study.

  human 0 · sources 6

• SS-31

  Approved medicine

  SS-31 is elamipretide, a cardiolipin-binding mitochondrial peptide approved by the FDA in September 2025 as Forzinity for Barth syndrome only. Marketed online for energy and aging uses it has not been approved for.

  human 3 · sources 5