Peptide library
A mechanism belongs in mechanism language, an animal model belongs in preclinical language, and a human trial belongs in human-evidence language. Every entry below keeps those apart, and states plainly where the evidence stops.
31 of 31 compounds
5-Amino-1MQ
No human data5-Amino-1MQ is a small molecule, not a peptide, that blocks the enzyme NNMT. It has been tested only in mice and cultured cells; there is no human data.
- human
- 0
- animal/preclinical
- 4
- reviews
- 1
- sources
- 6
AOD-9604
Early human dataA modified fragment of human growth hormone tested in six placebo-controlled trials with 893 adults; well tolerated, no IGF-1 rise, and no confirmed weight loss in its largest trial. Not FDA-approved; WADA-prohibited.
- human
- 1
- animal/preclinical
- 2
- reviews
- 1
- sources
- 6
BPC-157
Early human dataBPC-157 is a synthetic 15 amino acid peptide derived from a gastric juice protein. Three uncontrolled human studies in 30 people report self-rated benefit for knee pain and interstitial cystitis; its tendon and stomach healing results come from rats.
- human
- 3
- animal/preclinical
- 3
- reviews
- 1
- sources
- 8
CJC-1295 DAC
Early human dataCJC-1295 with DAC is an albumin-binding, long-acting GHRH analogue that raised GH and IGF-I for days in small 2006 trials in healthy adults. No outcome data; not approved.
- human
- 2
- animal/preclinical
- 2
- reviews
- 0
- sources
- 5
CJC-1295 no DAC
No human dataCJC-1295 no DAC (modified GRF 1-29) is the tetrasubstituted GHRH(1-29) fragment without the albumin-binding group. The cited human trials used the DAC form; none tested this one.
- human
- 2
- animal/preclinical
- 1
- reviews
- 0
- sources
- 5
DSIP
Early human dataDSIP is a nine-amino-acid peptide named in 1977 for a sleep effect never confirmed. A double-blind trial in insomniacs found no change in deep sleep, and the body's own DSIP-like material is lowest at night.
- human
- 3
- animal/preclinical
- 1
- reviews
- 1
- sources
- 7
Epitalon
Early human dataEpitalon is a synthetic pineal tetrapeptide (AEDG) with two small human studies, on retinal function and on melatonin markers, and independent evidence only in cell culture.
- human
- 1
- animal/preclinical
- 1
- reviews
- 1
- sources
- 4
GHK-Cu
No human dataGHK-Cu is a copper-binding tripeptide found naturally in human plasma and widely used in cosmetics. No human study of it is cited first hand; the best direct evidence is from fibroblast cultures and rat wound models.
- human
- 0
- animal/preclinical
- 3
- reviews
- 2
- sources
- 6
Glow
No human dataGLOW is a marketed blend of GHK-Cu, BPC-157 and TB-500. No source studied the blend itself in people, animals or cells; all cited research covers single components.
- human
- 0
- animal/preclinical
- 2
- reviews
- 1
- sources
- 5
Glutathione
Early human dataGlutathione is the body's main antioxidant tripeptide. Small oral trials show it can raise blood and cell levels, with conflicting marker results and no tested health outcomes; IV use has no controlled trial in the cited sources.
- human
- 4
- animal/preclinical
- 0
- reviews
- 1
- sources
- 6
IGF-1 LR3
No human dataAn engineered IGF-1 analogue designed to evade IGF binding proteins. Never tested in people; the human data nearby concerns natural IGF-I and cancer risk, and the approved unmodified hormone.
- human
- 2
- animal/preclinical
- 1
- reviews
- 1
- sources
- 7
Ipamorelin
Early human dataIpamorelin is a synthetic ghrelin-receptor peptide that releases growth hormone. Its human data are one volunteer pharmacology study and one Phase 2 bowel surgery trial that did not beat placebo.
- human
- 2
- animal/preclinical
- 1
- reviews
- 1
- sources
- 5
Kisspeptin-10
Early human dataKisspeptin-10 is the short active fragment of the kisspeptin family, acting above the pituitary on the reproductive hormone axis. Small human studies show acute LH and testosterone rises in healthy men.
- human
- 2
- animal/preclinical
- 1
- reviews
- 1
- sources
- 5
KPV
No human dataKPV is the Lys-Pro-Val tripeptide from the C-terminal end of alpha-MSH. There is no human data; it has been studied in cell lines, mouse colitis models and a rabbit cornea model.
- human
- 0
- animal/preclinical
- 3
- reviews
- 0
- sources
- 4
LL-37
Controlled human trialsLL-37 is the only human cathelicidin, an antimicrobial peptide tested topically in three randomised chronic-wound trials. The largest, a phase IIb in venous leg ulcers, found no benefit over placebo.
- human
- 3
- animal/preclinical
- 2
- reviews
- 1
- sources
- 8
MK-677
Controlled human trialsAn orally active non-peptide ghrelin mimetic that reliably raises growth hormone and IGF-1. In placebo-controlled trials it added fat-free mass in healthy older adults without improving strength or function.
- human
- 4
- animal/preclinical
- 1
- reviews
- 0
- sources
- 7
MOTS-C
No human dataMOTS-c is a 16 amino acid peptide encoded in mitochondrial DNA. Its metabolic and physical effects come from mice; in people it has been measured but not given in any cited study.
- human
- 0
- animal/preclinical
- 2
- reviews
- 3
- sources
- 6
NAD+
Early human dataNAD+ is a cellular coenzyme for energy metabolism and DNA-repair signalling. Trials of NAD+ itself are few, small and in hospital patients; most human data concern precursors such as NR, NMN and niacin.
- human
- 4
- animal/preclinical
- 0
- reviews
- 3
- sources
- 9
PEG-MGF
No human dataPEG-MGF is synthetic mechano growth factor, a 24 amino acid peptide named after an IGF-1 splice variant, with polyethylene glycol attached. No study in its sources gave it to a person.
- human
- 1
- animal/preclinical
- 1
- reviews
- 2
- sources
- 7
Pinealon
Early human dataPinealon is a three amino acid peptide (Glu-Asp-Arg) from a St. Petersburg family of bioregulators. Human data are limited to a 32-person study that also gave vesugen and a 72-patient report known only from its developers' review.
- human
- 1
- animal/preclinical
- 3
- reviews
- 1
- sources
- 7
PT-141
Approved medicineBremelanotide, sold as Vyleesi, is FDA-approved for acquired, generalized HSDD in premenopausal women. The label excludes men, postmenopausal women and use to enhance sexual performance.
- human
- 3
- animal/preclinical
- 0
- reviews
- 1
- sources
- 6
Retatrutide
Controlled human trialsRetatrutide is an investigational triple GIP, GLP-1 and glucagon agonist with completed Phase 3 obesity data, the strongest human evidence in this library. Not approved; filing expected 2027.
- human
- 3
- animal/preclinical
- 0
- reviews
- 1
- sources
- 5
Selank
Early human dataSelank is a synthetic tuftsin-derived heptapeptide developed in Moscow, studied in rats and in one 70-patient Russian trial where it was added to phenazepam.
- human
- 1
- animal/preclinical
- 3
- reviews
- 0
- sources
- 5
Semax
Early human dataSemax is a synthetic ACTH(4-7) plus Pro-Gly-Pro heptapeptide studied in Russia, with one randomised, open-label trial in 110 stroke survivors and rat stroke-model work.
- human
- 1
- animal/preclinical
- 2
- reviews
- 0
- sources
- 4
Sermorelin
Controlled human trialsSermorelin is GHRH(1-29), approved as Geref until 2009 for growth failure in growth-hormone-deficient children and for pituitary testing, with randomised paediatric trials and no controlled adult outcome data.
- human
- 12
- animal/preclinical
- 0
- reviews
- 2
- sources
- 18
SLU-PP-332
No human dataSLU-PP-332 is a small-molecule agonist of the estrogen-related receptors, not a peptide, studied as an exercise mimetic in mice and cell culture. No human data.
- human
- 0
- animal/preclinical
- 4
- reviews
- 0
- sources
- 5
SS-31
Approved medicineSS-31 is elamipretide, a cardiolipin-binding mitochondrial peptide approved by the FDA in September 2025 as Forzinity for Barth syndrome only. Marketed online for energy and aging uses it has not been approved for.
- human
- 3
- animal/preclinical
- 0
- reviews
- 1
- sources
- 5
TB-500
No human dataTB-500 is a synthetic seven-residue fragment of thymosin beta-4 (Ac-LKKTETQ) with no human data cited. The repair findings attached to its name come from the full-length protein in rats and cell culture.
- human
- 0
- animal/preclinical
- 2
- reviews
- 1
- sources
- 5
Tesamorelin
Approved medicineTesamorelin is a GHRH analog approved by the FDA in 2010 as EGRIFTA to reduce excess abdominal fat in HIV-infected adults with lipodystrophy. It is not a weight-loss drug.
- human
- 1
- animal/preclinical
- 0
- reviews
- 3
- sources
- 6
Thymosin Alpha 1
Controlled human trialsA 28 amino acid thymic peptide that did not reduce 28-day mortality in a 1,106-patient double-blind sepsis trial. Approved abroad as thymalfasin (Zadaxin); not approved in the United States.
- human
- 2
- animal/preclinical
- 0
- reviews
- 3
- sources
- 7
Thymulin
No human dataThymulin is a zinc-dependent thymic hormone. Its human data measured the body's own thymulin rising when zinc was restored; no cited study has given thymulin to a person.
- human
- 2
- animal/preclinical
- 1
- reviews
- 3
- sources
- 8
