Metabolic Modulators
This category covers peptides and related signaling compounds studied for their influence on metabolic regulation, mitochondrial function, and energy utilization within cells. Research often focuses on pathways affecting glucose metabolism, lipid oxidation, thermogenesis, and mitochondrial efficiency. These compounds are frequently explored in contexts involving metabolic flexibility, body composition regulation, energy expenditure, and cellular energy signaling networks.
5-Amino-1MQ
No human data5-Amino-1MQ is a small molecule, not a peptide, that blocks the enzyme NNMT. It has been tested only in mice and cultured cells; there is no human data.
human 0 · sources 6
AOD-9604
Early human dataA modified fragment of human growth hormone tested in six placebo-controlled trials with 893 adults; well tolerated, no IGF-1 rise, and no confirmed weight loss in its largest trial. Not FDA-approved; WADA-prohibited.
human 1 · sources 6
Kisspeptin-10
Early human dataKisspeptin-10 is the short active fragment of the kisspeptin family, acting above the pituitary on the reproductive hormone axis. Small human studies show acute LH and testosterone rises in healthy men.
human 2 · sources 5
NAD+
Early human dataNAD+ is a cellular coenzyme for energy metabolism and DNA-repair signalling. Trials of NAD+ itself are few, small and in hospital patients; most human data concern precursors such as NR, NMN and niacin.
human 4 · sources 9
Retatrutide
Controlled human trialsRetatrutide is an investigational triple GIP, GLP-1 and glucagon agonist with completed Phase 3 obesity data, the strongest human evidence in this library. Not approved; filing expected 2027.
human 3 · sources 5
SLU-PP-332
No human dataSLU-PP-332 is a small-molecule agonist of the estrogen-related receptors, not a peptide, studied as an exercise mimetic in mice and cell culture. No human data.
human 0 · sources 5
Tesamorelin
Approved medicineTesamorelin is a GHRH analog approved by the FDA in 2010 as EGRIFTA to reduce excess abdominal fat in HIV-infected adults with lipodystrophy. It is not a weight-loss drug.
human 1 · sources 6