Cognitive & Neuro
Peptides in this category relate to signaling systems involved in cognition, neuronal communication, and nervous-system adaptation. Research often examines pathways affecting neurotrophic factors, synaptic plasticity, neurotransmitter balance, stress-response signaling, and mitochondrial function within neural tissue. These compounds are discussed in educational contexts around focus, memory, mood-related signaling, neuroprotection research, and resilience of brain and peripheral nerve networks, with evidence varying by compound and study model.
DSIP
Early human dataDSIP is a nine-amino-acid peptide named in 1977 for a sleep effect never confirmed. A double-blind trial in insomniacs found no change in deep sleep, and the body's own DSIP-like material is lowest at night.
human 3 · sources 7
Pinealon
Early human dataPinealon is a three amino acid peptide (Glu-Asp-Arg) from a St. Petersburg family of bioregulators. Human data are limited to a 32-person study that also gave vesugen and a 72-patient report known only from its developers' review.
human 1 · sources 7
PT-141
Approved medicineBremelanotide, sold as Vyleesi, is FDA-approved for acquired, generalized HSDD in premenopausal women. The label excludes men, postmenopausal women and use to enhance sexual performance.
human 3 · sources 6
Selank
Early human dataSelank is a synthetic tuftsin-derived heptapeptide developed in Moscow, studied in rats and in one 70-patient Russian trial where it was added to phenazepam.
human 1 · sources 5
Semax
Early human dataSemax is a synthetic ACTH(4-7) plus Pro-Gly-Pro heptapeptide studied in Russia, with one randomised, open-label trial in 110 stroke survivors and rat stroke-model work.
human 1 · sources 4